Data on the effect of in utero exposure to polycyclic aromatic hydrocarbons on genome-wide patterns of DNA methylation in lung tissues
نویسندگان
چکیده
Data in this article depict patterns of methylation in lung tissues obtained from the offspring of B6129SF1/J dams and 129S1/SvImJ sires exposed in utero to benzo[a]pyrene (BaP) or dibenzo[def,p]chrysene (DBC) as compared to non-exposed offspring. Genome-wide methylation of lung tumors in adult offspring was determined using methylated DNA immunoprecipitation (MeDIP) with the NimbleGen mouse DNA methylation CpG island array. This data article refers to the research article "DNA methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons," [1] in which comprehensive data interpretation and analysis are provided.
منابع مشابه
DNA methylation in lung tissues of mouse offspring exposed in utero to polycyclic aromatic hydrocarbons.
Polycyclic aromatic hydrocarbons (PAHs) comprise an important class of environmental pollutants that are known to cause lung cancer in animals and are suspected lung carcinogens in humans. Moreover, evidence from cell-based studies points to PAHs as modulators of the epigenome. The objective of this work was to assess patterns of genome-wide DNA methylation in lung tissues of adult offspring in...
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عنوان ژورنال:
دوره 13 شماره
صفحات -
تاریخ انتشار 2017